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	Provedor de dados BJMBR (1) Autor Cheng,M-H. (1) Lin,J-H. (1) Wang,W-J. (1) Weng,C-S. (1) Palavra-chave Anti-inflammation (1) Endothelial cells (1) Hemodialysis fluid (1) LPS (1) Rosmarinic acid (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells BJMBR Wang,W-J.; Cheng,M-H.; Lin,J-H.; Weng,C-S.. Chronic systemic inflammation and repetitive damage of vascular endothelia by incompatible dialysis system are probable causes of cardiovascular disease in patients on dialysis. The present study aimed to assess in vitro biocompatibility and anti-inflammatory effect of hemodialysis fluid supplemented with rosmarinic acid (RA) using human umbilical vein endothelial cells (HUVEC). HUVECs (5×106 cells/mL) were pre-exposed to 1 μg/mL of lipopolysaccharides (LPS) and incubated with RA-supplemented hemodialysis fluid (HDF). Cytotoxicity was assessed qualitatively by morphologic assessment and quantitatively by MTT assay. Expressions of proinflammatory mediators were assessed using quantitative real-time PCR and production of NO was quantified. Phosphorylation of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Rosmarinic acid; Hemodialysis fluid; Anti-inflammation; Endothelial cells; LPS. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200606 Registros recuperados: 1 Primeira ... 1 ... Última

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